Tranexamic acid in primary total knee arthroplasty: ideal route of administration

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Which Route of Tranexamic Acid Administration is More Effective to Reduce Blood Loss Following Total Knee Arthroplasty?

  Background: The most appropriate route of tranexamic acid administration is controversial. In the current study, we compared the efficacy of intravenous (IV) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. Methods: One hundred twenty 120 patients were scheduled to undergo primary total knee arth...

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Tranexamic Acid Administration in Total Knee Arthroplasty Without Tourniquet

This open-access article is published and distributed under the Creative Commons Attribution NonCommercial No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article witho...

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Intraarticular Administration of Tranexamic Acid Following Total Knee Arthroplasty: A Case-control Study

Background:  Tranexamic acid (TXA) has received extensive attention in management of blood loss in orthopedic surgeries. However, the ideal method of TXA administration is still controversial. This study aims to determine whether intraarticular injection of TXA reduces blood loss after total knee arthroplasty (TKA).   Methods:  Through a retrospective case-control study consecutive TKA patients...

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Blood Loss and Transfusion After Topical Tranexamic Acid Administration in Primary Total Knee Arthroplasty.

There has been much debate and controversy about the safety and efficacy of the topical use of tranexamic acid in primary total knee arthroplasty (TKA). The purpose of this study was to perform a meta-analysis to evaluate whether there is less blood loss and lower rates of transfusion after topical tranexamic acid administration in primary TKA. A systematic review of the electronic databases Pu...

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Tranexamic Acid and Total Knee Arthroplasty

Total knee arthroplasty (TKA) is one of the most commonly performed elective orthopaedic procedures in the United States [1]. By 2030, the number is estimated to grow by 673% to 3.48 million TKAs performed a year [1]. TKA provides significant pain relief and improvement in quality of life [2]. However TKA surgery is not without complications. Of note is the risk of bleeding and requirement for ...

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ژورنال

عنوان ژورنال: Biomechanica Hungarica

سال: 2019

ISSN: 2060-0305

DOI: 10.17489/biohun/2019/1/05